Serum CXCL10, CXCL11, CXCL12, and CXCL14 chemokine patterns in patients with acute liver injury
نویسندگان
چکیده
منابع مشابه
Evaluation of CXCL10 and CXCL11 Genes in Patients with Celiac Disease by Specific Primer Paris
Background: Celiac Disease (CD) is a T cell-mediated disorder. Recent studies suggest the role of chemokines CXCL10 and CXCL11 to promote the arrival of cells into inflamed tissues and in lymphocytic recruitment in active CD. The aim of this study was to investigate the new specific primer pairs for analysis of human CXCL10 and CXCL11 genes in blood samples of CD patients by Polymerase Chain Re...
متن کاملEvaluation of CXCL10 and CXCL11 Genes in Patients with Celiac Disease by Specific Primer Paris
Background: Celiac Disease (CD) is a T cell-mediated disorder. Recent studies suggest the role of chemokines CXCL10 and CXCL11 to promote the arrival of cells into inflamed tissues and in lymphocytic recruitment in active CD. The aim of this study was to investigate the new specific primer pairs for analysis of human CXCL10 and CXCL11 genes in blood samples of CD patients by Polymerase Chain Re...
متن کاملEpithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
The chemokine receptor, CXC chemokine receptor 4 (CXCR4), is selective for CXC chemokine ligand 12 (CXCL12), is broadly expressed in blood and tissue cells, and is essential during embryogenesis and hematopoiesis. CXCL14 is a homeostatic chemokine with unknown receptor selectivity and preferential expression in peripheral tissues. Here, we demonstrate that CXCL14 synergized with CXCL12 in the i...
متن کاملDifferential Expression of CXCL1, CXCL9 CXCL10 and CXCL12 Chemokines in Alopecia Areata
Background: Alopecia Areata (AA) is a non-scarring, autoimmune disorder which causes hair loss. Inflammatory reactions are involved in hair loss of the scalp and/or body. The involvement of chemokine receptors in the pathogenesis of AA is well defined among which, CXCL1 acts on neutrophils and CXCL9, CXCL10 and CXCL12 and serve as T lymphocytes recruiters. Objective: To study the serum levels o...
متن کاملThe Serum Concentrations of Chemokine CXCL12 and Its Specific Receptor CXCR4 in Patients with Esophageal Cancer
OBJECTIVES Recent investigations have suggested that upregulated levels of inflammatory biomarkers, such as chemokines, may be associated with development of many malignancies, including esophageal cancer (EC). Based on our knowledge, this study is the first to assess the serum concentration of chemokine CXCL12 and its specific receptor CXCR4 in the diagnosis of EC patients. MATERIAL AND METH...
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ژورنال
عنوان ژورنال: Cytokine
سال: 2018
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2018.05.029